2026 Q1 FDA Reports

unique_aer_id_number	receive_date	drug	animal_species	outcome_medical_status	outcome_animals_affected	reaction	veddra_version	veddra_term_code	veddra_term_name	reaction_animals_affected	accuracy	is_core_fatal_code	is_review_fatal_code	treated_for_ae	number_of_animals_affected	number_of_animals_treated	primary_reporter	secondary_reporter	first_exposure_date	last_exposure_date	administered_by	route	dose	used_according_to_label	off_label_use	lot_number	lot_expiration	dosage_form	atc_vet_code	active_ingredients	manufacturer
USA-USFDACVM-2026-US-011204	20260312	MSK	Cat	Recovered/Normal	1	Corneal ulcer	21	415	Corneal ulcer	1	Actual	False	False	false	1	1	Other	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270201	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011204	20260312	MSK	Cat	Recovered/Normal	1	Application site scratching	21	26	Application site scratching	1	Actual	False	False	false	1	1	Other	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270201	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011204	20260312	MSK	Cat	Recovered/Normal	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270201	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008752	20260224	MSK	Cat	Died	1	Paraplegia	21	692	Paraplegia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260130	20260130	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008752	20260224	MSK	Cat	Died	1	Death	21	984	Death	1	Actual	True	False	false	1	1	Other	Animal Owner	20260130	20260130	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Ataxia	21	654	Ataxia	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Balance problem	21	372	Balance problem	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Head shake - behavioural disorder	21	2412	Head shake - behavioural disorder	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Falling	21	651	Falling	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Difficulty chewing	21	2450	Difficulty chewing	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Impaired hearing	21	1513	Impaired hearing	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Abnormal pupil light reflex	21	1097	Abnormal pupil light reflex	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Abnormal movement NOS	21	1131	Abnormal movement NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Muscle atrophy (see also Muscle wasting)	21	2470	Muscle atrophy (see also Muscle wasting)	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000100	20260105	MSK	Cat	Ongoing	1	Head tilt - neurological disorder (see also Head tilt - ear disorder)	21	2523	Head tilt - neurological disorder (see also Head tilt - ear disorder)	1	Actual	False	False	true	1	1	Other	Animal Owner	20251230	20251230	Other	Topical	{'numerator': '0.75', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Overdosed	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Not eating	21	1207	Not eating	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Not drinking	21	541	Not drinking	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Walking difficulty	21	1902	Walking difficulty	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Third eyelid protrusion	21	1105	Third eyelid protrusion	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005956	20260201	MSK	Cat	Recovered/Normal	1	Nasal cavity disorder NOS	21	1634	Nasal cavity disorder NOS	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260129	20260129	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013840	20260320	MSK	Cat	Ongoing	1	Gastrointestinal foreign body NOS	21	2562	Gastrointestinal foreign body NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260316	20260316	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012282	20260317	MSK	Cat	Outcome Unknown	1	Pyrexia	21	1031	Pyrexia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260314	20260314	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012282	20260317	MSK	Cat	Outcome Unknown	1	Stomach pain	21	1799	Stomach pain	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260314	20260314	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001152	20260114	MSK	Cat	Ongoing	1	Application site scratching	21	26	Application site scratching	1	Actual	False	False	true	1	1	Other	Animal Owner	20260114	20260114	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Hiding	21	2207	Hiding	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Facial swelling (see also Skin)	21	517	Facial swelling (see also Skin)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Elevated lactate	21	2852	Elevated lactate	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Low sodium-potassium ratio (Na:K ratio)	21	2630	Low sodium-potassium ratio (Na:K ratio)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Nasal discharge	21	871	Nasal discharge	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Low ionized calcium (Ca; Hypocalcaemia, ionized)	21	2686	Low ionized calcium (Ca; Hypocalcaemia, ionized)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Neutrophilia	21	168	Neutrophilia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Leukopenia NOS	21	164	Leukopenia NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Hypoalbuminaemia	21	1883	Hypoalbuminaemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Increased salivation	21	1533	Increased salivation	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Lying down	21	2743	Lying down	1	Actual	False	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005585	20260209	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Other	Animal Owner	20260205	20260205	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Elevated total bilirubin	21	2052	Elevated total bilirubin	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Abnormal ultrasound finding	21	2069	Abnormal ultrasound finding	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Digestive tract hypomotility	21	2163	Digestive tract hypomotility	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Elevated globulins	21	2556	Elevated globulins	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009378	20260302	MSK	Cat	Recovered/Normal	1	Muscle tremor	21	684	Muscle tremor	1	Actual	False	False	true	1	1	Other	Animal Owner	20260225	20260225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013836	20260319	MSK	Cat	Recovered/Normal	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Other	Veterinarian	20260318	20260318	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013836	20260319	MSK	Cat	Recovered/Normal	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Other	Veterinarian	20260318	20260318	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013836	20260319	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Other	Veterinarian	20260318	20260318	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013836	20260319	MSK	Cat	Recovered/Normal	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Other	Veterinarian	20260318	20260318	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006873	20260212	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228	20261130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006873	20260212	MSK	Cat	Outcome Unknown	1	Application site reddening	21	1332	Application site reddening	1	Actual	False	False	true	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228	20261130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006873	20260212	MSK	Cat	Outcome Unknown	1	Application site irritation	21	24	Application site irritation	1	Actual	False	False	true	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228	20261130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006873	20260212	MSK	Cat	Outcome Unknown	1	Application site itching	21	23	Application site itching	1	Actual	False	False	true	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228	20261130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001344	20260116	MSK	Cat	Outcome Unknown	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012579	20260317	MSK				Tubes, Leaking	11	99029	Tubes, Leaking			False	False				Other	Other								E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014197	20260322	MSK	Cat	Outcome Unknown	1	Fear/fearful	21	3062	Fear/fearful	1	Actual	False	False		1	1	Other	Other	20260322	20260322	Other	Oral	{'numerator': '10', 'numerator_unit': 'Milligram', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014197	20260322	MSK	Cat	Outcome Unknown	1	Administration error NOS	21	3035	Administration error NOS	1	Actual	False	False		1	1	Other	Other	20260322	20260322	Other	Oral	{'numerator': '10', 'numerator_unit': 'Milligram', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Urinary retention	21	737	Urinary retention	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Intestinal stasis	21	1066	Intestinal stasis	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Hypoalbuminaemia	21	1883	Hypoalbuminaemia	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008750	20260226	MSK	Cat	Ongoing	1	Hypokalaemia	21	2418	Hypokalaemia	1	Actual	False	False	true	1	1	Animal Owner	Other	20260222	20260222	Other	Topical	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006576	20260213	MSK	Cat	Outcome Unknown	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False		1	1	Other	Other	20260210	20260210	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006576	20260213	MSK	Cat	Outcome Unknown	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False		1	1	Other	Other	20260210	20260210	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006576	20260213	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False		1	1	Other	Other	20260210	20260210	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Vacant	21	2636	Vacant	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Fear/fearful	21	3062	Fear/fearful	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Circling - behavioural disorder (see also Neurological disorders)	21	2611	Circling - behavioural disorder (see also Neurological disorders)	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Pacing	21	2208	Pacing	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Anxiety	21	115	Anxiety	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Staring	21	2635	Staring	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Neurological disorder NOS	21	2728	Neurological disorder NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000214	20260105	MSK	Cat	Euthanized	1	Oliguria	21	711	Oliguria	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260103	20260103	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008430	20260225	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260130	20260130	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Disorientation	21	660	Disorientation	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Ataxia	21	654	Ataxia	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014093	20260323	MSK	Cat	Outcome Unknown	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Other	20260316	20260316	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003472	20260128	MSK	Cat	Ongoing	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False		1	1	Veterinarian	Other	20260114	20260114	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	2026-10	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012565	20260316	MSK	Cat	Ongoing	1	Application site discharge NOS	21	3051	Application site discharge NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260220	20260220	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270228	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012565	20260316	MSK	Cat	Ongoing	1	Application site reddening	21	1332	Application site reddening	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260220	20260220	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270228	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012565	20260316	MSK	Cat	Ongoing	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260220	20260220	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270228	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012565	20260316	MSK	Cat	Ongoing	1	Application site lesion	21	14	Application site lesion	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260220	20260220	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	20270228	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011050	20260312	MSK	Cat	Ongoing	1	Pacing	21	2208	Pacing	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260307	20260307	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011050	20260312	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260307	20260307	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011050	20260312	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260307	20260307	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011050	20260312	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260307	20260307	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003287	20260122	MSK	Cat	Ongoing	1	Diarrhoea	21	302	Diarrhoea	1	Actual	False	False		1	1	Veterinarian	Other	20260120	20260120	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003287	20260122	MSK	Cat	Ongoing	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False		1	1	Veterinarian	Other	20260120	20260120	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003287	20260122	MSK	Cat	Ongoing	1	Dazed	21	3109	Dazed	1	Actual	False	False		1	1	Veterinarian	Other	20260120	20260120	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003287	20260122	MSK	Cat	Ongoing	1	Pyrexia	21	1031	Pyrexia	1	Actual	False	False		1	1	Veterinarian	Other	20260120	20260120	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000770	20260108	MSK	Cat	Recovered/Normal	1	Bladder distension	21	2639	Bladder distension	1	Actual	False	False	true	1	1	Other	Animal Owner	20250507	20250507	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000770	20260108	MSK	Cat	Recovered/Normal	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Other	Animal Owner	20250507	20250507	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000770	20260108	MSK	Cat	Recovered/Normal	1	Elevated liver enzymes NOS	21	1942	Elevated liver enzymes NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20250507	20250507	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000770	20260108	MSK	Cat	Recovered/Normal	1	Blood in urine	21	1956	Blood in urine	1	Actual	False	False	true	1	1	Other	Animal Owner	20250507	20250507	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009635	20260305	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other									E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-010864	20260306	MSK	Cat	Ongoing	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260305	20260305	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-010864	20260306	MSK	Cat	Ongoing	1	Fever	21	1032	Fever	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260305	20260305	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-010864	20260306	MSK	Cat	Ongoing	1	Anisocoria	21	670	Anisocoria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260305	20260305	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-010864	20260306	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260305	20260305	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-010864	20260306	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260305	20260305	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Neurological disorder NOS	21	2728	Neurological disorder NOS	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Vertical nystagmus	21	2638	Vertical nystagmus	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Difficulty standing	21	2868	Difficulty standing	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Vocalisation	21	129	Vocalisation	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Weakness	21	1023	Weakness	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Groaning	21	2393	Groaning	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Lip licking	21	2096	Lip licking	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005905	20260210	MSK	Cat	Euthanized	1	Disorientation	21	660	Disorientation	1	Actual	False	False		1	1	Animal Owner	Other	20260108	20260108	Unknown	Topical				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Ptyalism	21	1075	Ptyalism	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Tremor	21	1852	Tremor	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Aggression	21	113	Aggression	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Leukocytosis NOS	21	163	Leukocytosis NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Neutrophilia	21	168	Neutrophilia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Eosinopenia	21	2862	Eosinopenia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Hypernatraemia	21	2511	Hypernatraemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Elevated cholesterol (total)	21	2266	Elevated cholesterol (total)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Eyes rolling back	21	2084	Eyes rolling back	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Elevated haematocrit	21	2856	Elevated haematocrit	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Disorientation	21	660	Disorientation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Urinary tract obstruction/blockage	21	2874	Urinary tract obstruction/blockage	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Anaemia NOS	21	142	Anaemia NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Other abnormal test result NOS	21	1221	Other abnormal test result NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Mydriasis	21	690	Mydriasis	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Acting tense	21	2206	Acting tense	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Mental confusion	21	1609	Mental confusion	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Twitching	21	686	Twitching	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Bradycardia	21	188	Bradycardia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Decreased heart rate	21	189	Decreased heart rate	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Haematuria	21	1967	Haematuria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003253	20260116	MSK	Cat	Outcome Unknown	1	Proteinuria	21	1961	Proteinuria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251023	20251023	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Hiding	21	2207	Hiding	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011914	20260312	MSK	Cat	Recovered/Normal	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E209227	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013330	20260317	MSK	Cat	Ongoing	1	Increased appetite	21	1530	Increased appetite	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260316	20260316	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E237960	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013330	20260317	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260316	20260316	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E237960	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012422	20260317	MSK	Cat	Ongoing	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False	true	1	1	Other	Animal Owner	20260305	20260305	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014109	20260323	MSK	Cat	Outcome Unknown	1	Tongue ulceration	21	290	Tongue ulceration	1	Actual	False	False		1	1	Other	Other	20251024	20251024	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014109	20260323	MSK	Cat	Outcome Unknown	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Other	Other	20251024	20251024	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014109	20260323	MSK	Cat	Outcome Unknown	1	Drooling	21	292	Drooling	1	Actual	False	False		1	1	Other	Other	20251024	20251024	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014109	20260323	MSK	Cat	Outcome Unknown	1	Stomatitis	21	300	Stomatitis	1	Actual	False	False		1	1	Other	Other	20251024	20251024	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008461	20260225	MSK	Cat	Outcome Unknown	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008461	20260225	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008461	20260225	MSK	Cat	Outcome Unknown	1	Not drinking	21	541	Not drinking	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Appetite loss	21	997	Appetite loss	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Hypersalivation	21	293	Hypersalivation	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Disoriented state	21	1418	Disoriented state	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Impaired vision	21	407	Impaired vision	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Elevated creatine-kinase (CK)	21	2245	Elevated creatine-kinase (CK)	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Oral ulceration	21	301	Oral ulceration	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Circling - neurological disorder (see also Behavioural disorders)	21	652	Circling - neurological disorder (see also Behavioural disorders)	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004234	20260120	MSK	Cat	Outcome Unknown	1	Limb weakness	21	1121	Limb weakness	1	Actual	False	False	true	1	1	Other	Veterinarian	20260105	20260112	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Indication Off-Label', 'Other off label issue']	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Not defecating	21	3066	Not defecating	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008601	20260225	MSK	Cat	Ongoing	1	Application site reddening	21	1332	Application site reddening	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Open mouth breathing	21	1172	Open mouth breathing	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Unable to walk	21	3017	Unable to walk	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Balance impaired	21	1341	Balance impaired	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Abnormal posture NOS	21	1132	Abnormal posture NOS	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Arthritis	21	569	Arthritis	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Twitching	21	686	Twitching	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008768	20260225	MSK	Cat	Ongoing	1	Unresponsive to stimuli	21	2247	Unresponsive to stimuli	1	Actual	False	False	false	1	1	Other	Animal Owner	20260224	20260224	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	20261020	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004528	20260204	MSK	Cat	Outcome Unknown	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260101	20260101	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004676	20260204	MSK	Cat	Died	1	Death	21	984	Death	1	Actual	True	False		1	1	Other	Animal Owner	20260112	20260112	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Hallucination	21	117	Hallucination	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Uncomfortable	21	2499	Uncomfortable	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Dazed	21	3109	Dazed	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013520	20260321	MSK	Cat	Ongoing	1	Grand mal seizure	21	2727	Grand mal seizure	1	Actual	False	False		1	1	Veterinarian	Other	20260318	20260318	Unknown	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013856	20260323	MSK	Cat	Recovered/Normal	1	Tongue ulceration	21	290	Tongue ulceration	1	Actual	False	False	true	1	1	Other	Other	20260312	20260312	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013871	20260323	MSK	Cat	Recovered/Normal	1	Tongue ulceration	21	290	Tongue ulceration	1	Actual	False	False	true	1	1	Other	Other	20260312	20260312	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011199	20260312	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260129	20260129	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E226220	20270101	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Emesis (multiple)	21	2082	Emesis (multiple)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Malodour	21	908	Malodour	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Decreased bowel movements	21	1939	Decreased bowel movements	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Weight gain	21	1050	Weight gain	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Anaemia NOS	21	142	Anaemia NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Bilirubinuria	21	2175	Bilirubinuria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Glucosuria	21	1960	Glucosuria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Neutrophilia	21	168	Neutrophilia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Sick euthyroid syndrome	21	2507	Sick euthyroid syndrome	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Elevated serum alkaline phosphatase (ALP)	21	2055	Elevated serum alkaline phosphatase (ALP)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Elevated alanine aminotransferase (ALT)	21	2050	Elevated alanine aminotransferase (ALT)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Elevated total bilirubin	21	2052	Elevated total bilirubin	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Elevated blood urea nitrogen (BUN)	21	2047	Elevated blood urea nitrogen (BUN)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003346	20260127	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Veterinarian	Animal Owner	20251106	20251106	Unknown	Topical				NOT GIVEN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005924	20260210	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	true	1	1	Other	Other	20260102	20260102	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005924	20260210	MSK	Cat	Outcome Unknown	1	Application site pruritus	21	25	Application site pruritus	1	Actual	False	False	true	1	1	Other	Other	20260102	20260102	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004624	20260130	MSK	Cat	Outcome Unknown	1	Hypersalivation	21	293	Hypersalivation	1	Actual	False	False		1	1	Other	Animal Owner	20260126	20260126	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E173270	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004624	20260130	MSK	Cat	Outcome Unknown	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False		1	1	Other	Animal Owner	20260126	20260126	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E173270	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004624	20260130	MSK	Cat	Outcome Unknown	1	Erythema (for urticaria see Immune SOC)	21	948	Erythema (for urticaria see Immune SOC)	1	Actual	False	False		1	1	Other	Animal Owner	20260126	20260126	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E173270	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004624	20260130	MSK	Cat	Outcome Unknown	1	Pruritus	21	960	Pruritus	1	Actual	False	False		1	1	Other	Animal Owner	20260126	20260126	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E173270	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004624	20260130	MSK	Cat	Outcome Unknown	1	Mental confusion	21	1609	Mental confusion	1	Actual	False	False		1	1	Other	Animal Owner	20260126	20260126	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E173270	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006824	20260216	MSK	Cat	Recovered/Normal	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006824	20260216	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012176	20260317	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other	Other								E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004497	20260122	MSK	Cat	Outcome Unknown	2	Hyperthermia	21	1014	Hyperthermia	2	Actual	False	False	true	2	2	Other	Other	20260122	20260122	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003471	20260126	MSK	Cat	Outcome Unknown	2	Unclassifiable adverse event	21	2190	Unclassifiable adverse event	2	Estimated	False	False		2	2	Other	Other	20260101	20260101	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003471	20260126	MSK	Cat	Outcome Unknown	2	Neurological disorder NOS	21	2728	Neurological disorder NOS	2	Estimated	False	False		2	2	Other	Other	20260101	20260101	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003471	20260126	MSK	Cat	Outcome Unknown	2	Hyperthermia	21	1014	Hyperthermia	2	Estimated	False	False		2	2	Other	Other	20260101	20260101	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012218	20260312	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Oral		false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012218	20260312	MSK	Cat	Outcome Unknown	1	Accidental exposure	21	3034	Accidental exposure	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Oral		false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Restlessness	21	119	Restlessness	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Agitation	21	121	Agitation	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Difficulty standing	21	2868	Difficulty standing	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Stumbling gait	21	657	Stumbling gait	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006579	20260213	MSK	Cat	Recovered/Normal	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Other	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013634	20260319	MSK	Cat	Outcome Unknown	5	Dysphoria	21	2531	Dysphoria	3	Estimated	False	False		5	5	Other	Veterinarian	20260101	20260101	Veterinarian	Transdermal		false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013634	20260319	MSK	Cat	Outcome Unknown	5	Anorexia	21	996	Anorexia	3	Estimated	False	False		5	5	Other	Veterinarian	20260101	20260101	Veterinarian	Transdermal		false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013634	20260319	MSK	Cat	Outcome Unknown	5	Hyperactivity	21	118	Hyperactivity	2	Actual	False	False		5	5	Other	Veterinarian	20260101	20260101	Veterinarian	Transdermal		false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Unsteady gait	21	1858	Unsteady gait	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Pacing	21	2208	Pacing	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Blindness	21	406	Blindness	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Weakness	21	1023	Weakness	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Not drinking	21	541	Not drinking	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Elevated liver enzymes NOS	21	1942	Elevated liver enzymes NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Neurological disorder NOS	21	2728	Neurological disorder NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Cardiac enlargement	21	204	Cardiac enlargement	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Cerebral oedema	21	635	Cerebral oedema	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Encephalopathy NOS	21	666	Encephalopathy NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Elevated bile acids	21	2051	Elevated bile acids	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Other abnormal test result NOS	21	1221	Other abnormal test result NOS	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Decreased blood urea nitrogen (BUN) or creatinine	21	2702	Decreased blood urea nitrogen (BUN) or creatinine	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007175	20260212	MSK	Cat	Euthanized	1	Hypokalaemia	21	2418	Hypokalaemia	1	Actual	False	False		1	1	Other	Animal Owner	20260205	20260205	Other	Oral	{'numerator': '1', 'numerator_unit': 'tablet', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Adipsia	21	542	Adipsia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Lateral recumbency	21	1135	Lateral recumbency	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Hypothermia	21	1015	Hypothermia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Fluid in abdomen NOS	21	2011	Fluid in abdomen NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Hyperkalaemia	21	1944	Hyperkalaemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Elevated creatinine	21	2048	Elevated creatinine	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Elevated blood urea nitrogen (BUN)	21	2047	Elevated blood urea nitrogen (BUN)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Hyperphosphataemia	21	2046	Hyperphosphataemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Interstitial nephritis	21	715	Interstitial nephritis	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Nephropathy	21	717	Nephropathy	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Renal disorder NOS	21	719	Renal disorder NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Ureteric disorder	21	724	Ureteric disorder	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Pulmonary congestion	21	843	Pulmonary congestion	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Pulmonary emphysema	21	845	Pulmonary emphysema	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Pulmonary oedema	21	848	Pulmonary oedema	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002119	20260108	MSK	Cat	Euthanized	1	Necropsy performed	21	2142	Necropsy performed	1	Actual	False	False	true	1	1	Other	Animal Owner	20260105	20260105	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004926	20260205	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False		1	1	Veterinarian	Other	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004926	20260205	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Veterinarian	Other	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Oliguria	21	711	Oliguria	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Neutrophilia	21	168	Neutrophilia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Reluctant to move	21	1025	Reluctant to move	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Elevated temperature	21	1033	Elevated temperature	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Hypophosphataemia	21	2242	Hypophosphataemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Low creatinine	21	2701	Low creatinine	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Hypocalcaemia	21	2685	Hypocalcaemia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011407	20260309	MSK	Cat	Recovered/Normal	1	Low blood urea nitrogen (BUN)	21	2700	Low blood urea nitrogen (BUN)	1	Actual	False	False	true	1	1	Other	Animal Owner	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Dullness	21	126	Dullness	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Anaemia NOS	21	142	Anaemia NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Cardiac disorder NOS	21	202	Cardiac disorder NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Heart murmur	21	213	Heart murmur	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Pale mucous membrane	21	222	Pale mucous membrane	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Ataxia	21	654	Ataxia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Oliguria	21	711	Oliguria	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Renal failure	21	720	Renal failure	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Inappetence	21	999	Inappetence	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Ascites	21	1030	Ascites	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Third eyelid protrusion	21	1105	Third eyelid protrusion	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Lateral recumbency	21	1135	Lateral recumbency	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Acute renal failure	21	1159	Acute renal failure	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Prolonged capillary refill time	21	1937	Prolonged capillary refill time	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Splenic neoplasm NOS	21	1977	Splenic neoplasm NOS	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Head bobbing	21	2022	Head bobbing	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Elevated blood urea nitrogen (BUN)	21	2047	Elevated blood urea nitrogen (BUN)	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Elevated creatinine	21	2048	Elevated creatinine	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Abnormal radiograph finding	21	2070	Abnormal radiograph finding	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Azotaemia	21	2182	Azotaemia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Decreased packed cell volume (PCV)	21	2215	Decreased packed cell volume (PCV)	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Dull	21	2274	Dull	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008769	20260228	MSK	Cat	Euthanized	1	Hypernatraemia	21	2511	Hypernatraemia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260217	20260217	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Hypersalivation	21	293	Hypersalivation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Hypoglycaemia	21	1947	Hypoglycaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Hypotension	21	228	Hypotension	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Abnormal ultrasound finding	21	2069	Abnormal ultrasound finding	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Hiding	21	2207	Hiding	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Hypothermia	21	1015	Hypothermia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Neutropenia	21	167	Neutropenia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Diarrhoea	21	302	Diarrhoea	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012294	20260316	MSK	Cat	Ongoing	1	Soft stool	21	3069	Soft stool	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NP		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Unable to focus	21	1856	Unable to focus	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Decreased appetite	21	998	Decreased appetite	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009780	20260302	MSK	Cat	Ongoing	1	Weight loss	21	1043	Weight loss	1	Actual	False	False	false	1	1	Animal Owner	Other	20260120	20260120	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009363	20260226	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260220	20260220	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E209228	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009363	20260226	MSK	Cat	Recovered/Normal	1	Hair loss NOS	21	1507	Hair loss NOS	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260220	20260220	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E209228	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009363	20260226	MSK	Cat	Recovered/Normal	1	Hyperaesthesia	21	706	Hyperaesthesia	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260220	20260220	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E209228	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009363	20260226	MSK	Cat	Recovered/Normal	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260220	20260220	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E209228	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Polyphagia	21	137	Polyphagia	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Pacing	21	2208	Pacing	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Unsteady gait	21	1858	Unsteady gait	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002197	20260114	MSK	Cat	Ongoing	1	Staring	21	2635	Staring	1	Actual	False	False	false	1	1	Animal Owner	Other	20260113	20260113	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003345	20260123	MSK	Cat	Ongoing	1	Mydriasis	21	690	Mydriasis	1	Actual	False	False		1	1	Veterinarian	Other	20260121	20260121	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	2026-10	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003345	20260123	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Veterinarian	Other	20260121	20260121	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	2026-10	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003345	20260123	MSK	Cat	Ongoing	1	Hiding	21	2207	Hiding	1	Actual	False	False		1	1	Veterinarian	Other	20260121	20260121	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	2026-10	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003345	20260123	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False		1	1	Veterinarian	Other	20260121	20260121	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E206974	2026-10	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004232	20260129	MSK	Cat	Died	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	false	1	1	Veterinarian	Other	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004232	20260129	MSK	Cat	Died	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Veterinarian	Other	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004232	20260129	MSK	Cat	Died	1	Loss of voluntary movement	21	1597	Loss of voluntary movement	1	Actual	False	False	false	1	1	Veterinarian	Other	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004232	20260129	MSK	Cat	Died	1	Death	21	984	Death	1	Actual	True	False	false	1	1	Veterinarian	Other	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Decreased appetite	21	998	Decreased appetite	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Listless	21	1022	Listless	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Stumbling gait	21	657	Stumbling gait	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Arched back	21	2275	Arched back	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Abnormal posture	21	2395	Abnormal posture	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Spinal pain NOS	21	3104	Spinal pain NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Knuckling	21	578	Knuckling	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Slow reflexes	21	674	Slow reflexes	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Reduced responses	21	1021	Reduced responses	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Staring	21	2635	Staring	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Elevated temperature	21	1033	Elevated temperature	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Stiff gait	21	1950	Stiff gait	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009572	20260303	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260302	20260302	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Other off label issue	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014171	20260312	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014171	20260312	MSK	Cat	Outcome Unknown	1	Gait abnormality	21	1989	Gait abnormality	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014171	20260312	MSK	Cat	Outcome Unknown	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014171	20260312	MSK	Cat	Outcome Unknown	1	Monoparesis (paralysis of limb)	21	1617	Monoparesis (paralysis of limb)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260311	20260311	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006876	20260205	MSK	Cat	Ongoing	1	Head twitching	21	3110	Head twitching	1	Actual	False	False	false	1	1	Other	Animal Owner	20260202	20260202	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012588	20260316	MSK	Cat	Outcome Unknown	1	Application site lesion	21	14	Application site lesion	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260119	20260119	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E243170	20270430	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012588	20260316	MSK	Cat	Outcome Unknown	1	Application site inflammation	21	13	Application site inflammation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260119	20260119	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E243170	20270430	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012588	20260316	MSK	Cat	Outcome Unknown	1	Application site thickening	21	2515	Application site thickening	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260119	20260119	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E243170	20270430	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012588	20260316	MSK	Cat	Outcome Unknown	1	Application site irritation	21	24	Application site irritation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260119	20260119	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E243170	20270430	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005687	20260207	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	true	1	1	Other	Other	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	20270101	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005687	20260207	MSK	Cat	Ongoing	1	Urinary retention	21	737	Urinary retention	1	Actual	False	False	true	1	1	Other	Other	20260206	20260206	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E220855	20270101	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000104	20260106	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other									E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003288	20260127	MSK	Cat	Ongoing	1	Application site scratching	21	26	Application site scratching	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260113	20260113	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003288	20260127	MSK	Cat	Ongoing	1	Application site lump	21	21	Application site lump	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260113	20260113	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003288	20260127	MSK	Cat	Ongoing	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260113	20260113	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008024	20260220	MSK	Cat	Died	2	Unclassifiable adverse event	21	2190	Unclassifiable adverse event	2	Estimated	False	False		2	2	Animal Owner	Other	20260101	20260101	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008024	20260220	MSK	Cat	Died	2	Unexplained death	21	985	Unexplained death	2	Estimated	True	False		2	2	Animal Owner	Other	20260101	20260101	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Blinking	21	1101	Blinking	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Agitation	21	121	Agitation	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Sedation prolonged	21	1903	Sedation prolonged	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Respiratory tract disorder NOS	21	1180	Respiratory tract disorder NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Staring	21	2635	Staring	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Not urinating	21	2520	Not urinating	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Decreased activity	21	2039	Decreased activity	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Tracheal obstruction	21	880	Tracheal obstruction	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Ataxia	21	654	Ataxia	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Falling	21	651	Falling	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Unable to stand	21	653	Unable to stand	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003535	20260121	MSK	Cat	Ongoing	1	Decreased bowel movements	21	1939	Decreased bowel movements	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E249684	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Localised hair loss	21	1581	Localised hair loss	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Reddening of the skin	21	946	Reddening of the skin	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Rubbing	21	2496	Rubbing	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Pruritus	21	960	Pruritus	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006828	20260213	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260213	20260213	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E249681	20270531	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	Sedation	21	111	Sedation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	Decreased haematocrit	21	2853	Decreased haematocrit	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	Blood clot	21	153	Blood clot	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	Profuse bleeding	21	178	Profuse bleeding	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	Nasal bleeding	21	863	Nasal bleeding	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001964	20260114	MSK	Cat	Ongoing	1	High blood pressure	21	225	High blood pressure	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004299	20260203	MSK				Underfilling, Package	11	99030	Underfilling, Package			False	False				Other									E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003627	20260128	MSK	Cat	Recovered/Normal	1	Application site pustule	21	27	Application site pustule	1	Actual	False	False	true	1	1	Other	Other	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		3226220	20270130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003627	20260128	MSK	Cat	Recovered/Normal	1	Application site ulcer	21	35	Application site ulcer	1	Actual	False	False	true	1	1	Other	Other	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		3226220	20270130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003627	20260128	MSK	Cat	Recovered/Normal	1	Application site scab	21	15	Application site scab	1	Actual	False	False	true	1	1	Other	Other	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		3226220	20270130	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Panting	21	855	Panting	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Staring	21	2635	Staring	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Inappropriate urination	21	124	Inappropriate urination	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Biting -aggression (see also Skin and appendages disorders)	21	112	Biting -aggression (see also Skin and appendages disorders)	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Hissing	21	2754	Hissing	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Hiding	21	2207	Hiding	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Growling	21	2755	Growling	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Heavy breathing	21	2776	Heavy breathing	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Increased drinking	21	3130	Increased drinking	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Tachypnoea	21	854	Tachypnoea	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Abnormal breathing	21	837	Abnormal breathing	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Fear/fearful	21	3062	Fear/fearful	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Abnormal heart sound	21	3154	Abnormal heart sound	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Pain NOS	21	1012	Pain NOS	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Fever	21	1032	Fever	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Abnormal radiograph finding	21	2070	Abnormal radiograph finding	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Aggression	21	113	Aggression	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Weight loss	21	1043	Weight loss	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007423	20260217	MSK	Cat	Ongoing	1	Purulent lesion(s)	21	1193	Purulent lesion(s)	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260216	20260216	Other	Topical	{'numerator': '2.50', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002602	20260120	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Veterinarian	Veterinarian	20240101	20240101	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004923	20260204	MSK	Cat	Ongoing	1	Hallucination	21	117	Hallucination	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004923	20260204	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004923	20260204	MSK	Cat	Ongoing	1	Falling	21	651	Falling	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-004923	20260204	MSK	Cat	Ongoing	1	Locomotor disturbance	21	1248	Locomotor disturbance	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260203	20260203	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001133	20260113	MSK	Cat	Ongoing	1	Pale mucous membrane	21	222	Pale mucous membrane	1	Actual	False	False	true	1	1	Other	Animal Owner	20260113	20260113	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001133	20260113	MSK	Cat	Ongoing	1	Decreased heart rate	21	189	Decreased heart rate	1	Actual	False	False	true	1	1	Other	Animal Owner	20260113	20260113	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001133	20260113	MSK	Cat	Ongoing	1	Hypothermia	21	1015	Hypothermia	1	Actual	False	False	true	1	1	Other	Animal Owner	20260113	20260113	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Pacing	21	2208	Pacing	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Hallucination	21	117	Hallucination	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Limb weakness	21	1121	Limb weakness	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Not drinking	21	541	Not drinking	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007432	20260205	MSK	Cat	Recovered/Normal	1	Not defecating	21	3066	Not defecating	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20251205	20251205	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007448	20260219	MSK	Cat	Ongoing	10	Unclassifiable adverse event	21	2190	Unclassifiable adverse event	10	Actual	False	False		10	10	Veterinarian	Other	20260101	20260101	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002033	20260108	MSK	Cat	Outcome Unknown	1	Lack of efficacy - NOS	21	1039	Lack of efficacy - NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260107	20260107	Animal Owner	Unknown				E209228	2026-11	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Open mouth breathing	21	1172	Open mouth breathing	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Agitation	21	121	Agitation	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012021	20260312	MSK	Cat	Ongoing	1	Heavy breathing	21	2776	Heavy breathing	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260312	20260312	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Urinary retention	21	737	Urinary retention	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Constipation	21	267	Constipation	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Restlessness	21	119	Restlessness	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011414	20260313	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Other	Animal Owner	20260220	20260220	Unknown	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E237960	2027-03	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011055	20260312	MSK	Cat	Recovered/Normal	5	Dysphoria	21	2531	Dysphoria	5	Estimated	False	False	false	5	100	Veterinarian	Other	20260101	20260101	Unknown	Unknown		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007434	20260218	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260210	20260210	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000167	20260102	MSK	Cat	Ongoing	1	Limpness	21	2252	Limpness	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20251229	20251229	Veterinarian	Topical		false	['Overdosed', 'Treatment regimen Off-Label']	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000167	20260102	MSK	Cat	Ongoing	1	Increased appetite	21	1530	Increased appetite	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20251229	20251229	Veterinarian	Topical		false	['Overdosed', 'Treatment regimen Off-Label']	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000167	20260102	MSK	Cat	Ongoing	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20251229	20251229	Veterinarian	Topical		false	['Overdosed', 'Treatment regimen Off-Label']	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000167	20260102	MSK	Cat	Ongoing	1	Sedation	21	111	Sedation	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20251229	20251229	Veterinarian	Topical		false	['Overdosed', 'Treatment regimen Off-Label']	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000167	20260102	MSK	Cat	Ongoing	1	Sleepiness - neurological disorder	21	127	Sleepiness - neurological disorder	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20251229	20251229	Veterinarian	Topical		false	['Overdosed', 'Treatment regimen Off-Label']	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007430	20260219	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260215	20260215	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007430	20260219	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260215	20260215	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007430	20260219	MSK	Cat	Ongoing	1	Quiet	21	2645	Quiet	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260215	20260215	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000110	20260106	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other	Other								E182577	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003241	20260123	MSK	Cat	Recovered/Normal	1	Urinary retention	21	737	Urinary retention	1	Actual	False	False	true	1	1	Other	Animal Owner	20250917	20250917	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003241	20260123	MSK	Cat	Recovered/Normal	1	Sleep disturbance NOS	21	141	Sleep disturbance NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20250917	20250917	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000908	20260112	MSK	Cat	Ongoing	1	Corneal ulcer	21	415	Corneal ulcer	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20251225	20251225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000908	20260112	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20251225	20251225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000908	20260112	MSK	Cat	Ongoing	1	Temporary blindness	21	1829	Temporary blindness	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20251225	20251225	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Weight loss	21	1043	Weight loss	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Dermatitis	21	932	Dermatitis	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Tachycardia	21	192	Tachycardia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Excessive chewing, licking and/or grooming	21	1974	Excessive chewing, licking and/or grooming	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007178	20260212	MSK	Cat	Ongoing	1	Not urinating	21	2520	Not urinating	1	Actual	False	False	true	1	1	Animal Owner	Veterinarian	20260115	20260115	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED, NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009881	20260303	MSK	Cat	Recovered/Normal	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009881	20260303	MSK	Cat	Recovered/Normal	1	Anxiety	21	115	Anxiety	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260303	20260303	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Hind limb paresis	21	1153	Hind limb paresis	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Weakness	21	1023	Weakness	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Weight loss	21	1043	Weight loss	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Arched back	21	2275	Arched back	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Ataxia	21	654	Ataxia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008760	20260223	MSK	Cat	Ongoing	1	Cardiomyopathy	21	205	Cardiomyopathy	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260219	20260219	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008201	20260224	MSK	Cat	Ongoing	1	Excitation	21	120	Excitation	1	Actual	False	False	false	1	1	Other	Animal Owner	20260223	20260223	Other	Topical	{'numerator': '0.25', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E243170	2027-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008201	20260224	MSK	Cat	Ongoing	1	Agitation	21	121	Agitation	1	Actual	False	False	false	1	1	Other	Animal Owner	20260223	20260223	Other	Topical	{'numerator': '0.25', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E243170	2027-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008201	20260224	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Other	Animal Owner	20260223	20260223	Other	Topical	{'numerator': '0.25', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E243170	2027-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008201	20260224	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Other	Animal Owner	20260223	20260223	Other	Topical	{'numerator': '0.25', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	['Underdosed', 'Treatment regimen Off-Label']	E243170	2027-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013262	20260319	MSK	Cat	Recovered/Normal	1	Laboured breathing	21	1171	Laboured breathing	1	Actual	False	False	true	1	1	Veterinarian	Other	20260318	20260318	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013262	20260319	MSK	Cat	Recovered/Normal	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Veterinarian	Other	20260318	20260318	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007125	20260217	MSK	Cat	Ongoing	1	Application site reddening	21	1332	Application site reddening	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260202	20260202	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960	20270331	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007125	20260217	MSK	Cat	Ongoing	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260202	20260202	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960	20270331	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007125	20260217	MSK	Cat	Ongoing	1	Application site scab	21	15	Application site scab	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260202	20260202	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960	20270331	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007125	20260217	MSK	Cat	Ongoing	1	Application site dermatitis	21	1934	Application site dermatitis	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260202	20260202	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E237960	20270331	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014253	20260324	MSK	Cat	Recovered/Normal	4	Hiding	21	2207	Hiding	1	Actual	False	False		4	4	Veterinarian	Other	20260301	20260301	Other	Topical		false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014253	20260324	MSK	Cat	Recovered/Normal	4	Unclassifiable adverse event	21	2190	Unclassifiable adverse event	3	Actual	False	False		4	4	Veterinarian	Other	20260301	20260301	Other	Topical		false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012013	20260313	MSK	Cat	Ongoing	1	Febrile	21	1034	Febrile	1	Actual	False	False		1	1	Veterinarian	Other	20260313	20260313	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012013	20260313	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False		1	1	Veterinarian	Other	20260313	20260313	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Grooming disorder	21	1975	Grooming disorder	2	Estimated	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Behavioural disorder NOS	21	116	Behavioural disorder NOS	2	Estimated	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Reduced faecal output	21	2678	Reduced faecal output	8	Actual	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Appetite loss	21	997	Appetite loss	8	Actual	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Oliguria	21	711	Oliguria	8	Actual	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005845	20260209	MSK	Rabbit	Recovered/Normal	8	Decreased drinking	21	2500	Decreased drinking	4	Estimated	False	False	true	8	8	Other	Other	20250701	20250721	Unknown	Topical		false	Species Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Elevated temperature	21	1033	Elevated temperature	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Nervous	21	3063	Nervous	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Not defecating	21	3066	Not defecating	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Not urinating	21	2520	Not urinating	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005597	20260210	MSK	Cat	Ongoing	1	Administration error NOS	21	3035	Administration error NOS	1	Actual	False	False		1	1	Veterinarian	Animal Owner	20260209	20260209	Other	Oral	{'numerator': '0.20', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Route Off-Label	ASKED NOT KNOWN		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007191	20260210	MSK	Cat	Outcome Unknown	1	Application site hair loss	21	3	Application site hair loss	1	Actual	False	False	false	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007191	20260210	MSK	Cat	Outcome Unknown	1	Application site reddening	21	1332	Application site reddening	1	Actual	False	False	false	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007191	20260210	MSK	Cat	Outcome Unknown	1	Application site ulcer	21	35	Application site ulcer	1	Actual	False	False	false	1	1	Other	Animal Owner	20260206	20260206	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002041	20260120	MSK				Tubes, Leaking	11	99029	Tubes, Leaking			False	False				Other	Other								E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Vomiting	21	334	Vomiting	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	High pancreatic-specific lipase	21	2692	High pancreatic-specific lipase	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Neutrophilia	21	168	Neutrophilia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Pancreatitis NOS	21	1891	Pancreatitis NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Leukocytosis NOS	21	163	Leukocytosis NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Depression	21	1024	Depression	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Elevated gamma-glutamyl transferase (GGT)	21	2238	Elevated gamma-glutamyl transferase (GGT)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Azotaemia	21	2182	Azotaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Anaemia NOS	21	142	Anaemia NOS	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Hypoalbuminaemia	21	1883	Hypoalbuminaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Abdominal effusion	21	2164	Abdominal effusion	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Hyperglycaemia	21	1946	Hyperglycaemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Elevated symmetrical dimethylarginine (SDMA)	21	2583	Elevated symmetrical dimethylarginine (SDMA)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Elevated blood urea nitrogen (BUN)	21	2047	Elevated blood urea nitrogen (BUN)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Elevated creatinine	21	2048	Elevated creatinine	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Hyponatremia	21	2512	Hyponatremia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Hypochloraemia	21	2578	Hypochloraemia	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Low serum alkaline phosphatase (ALP)	21	2690	Low serum alkaline phosphatase (ALP)	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Decreased red blood cell count	21	2157	Decreased red blood cell count	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Decreased haemoglobin	21	2214	Decreased haemoglobin	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014358	20260316	MSK	Cat	Recovered/Normal	1	Proteinuria	21	1961	Proteinuria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Skin and tissue infection NOS	21	1755	Skin and tissue infection NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013633	20260319	MSK	Cat	Recovered/Normal	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False	true	1	1	Other	Veterinarian	20260310	20260310	Veterinarian	Transdermal	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Constipation	21	267	Constipation	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Inappropriate defecation	21	123	Inappropriate defecation	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Death by euthanasia	21	981	Death by euthanasia	1	Actual	True	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Vestibular disorder NOS	21	373	Vestibular disorder NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Disorientation	21	660	Disorientation	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Fear/fearful	21	3062	Fear/fearful	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Walking difficulty	21	1902	Walking difficulty	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Weakness	21	1023	Weakness	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Anorexia	21	996	Anorexia	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Dehydration	21	1208	Dehydration	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Neurological symptoms NOS	21	1648	Neurological symptoms NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Collapse NOS (see also Cardio-vascular and Neurological disorders)	21	1001	Collapse NOS (see also Cardio-vascular and Neurological disorders)	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Head tilt - neurological disorder (see also Head tilt - ear disorder)	21	2523	Head tilt - neurological disorder (see also Head tilt - ear disorder)	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Balance problem	21	372	Balance problem	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Vocalisation	21	129	Vocalisation	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Staring	21	2635	Staring	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Pawing	21	2592	Pawing	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Excessive thirst	21	544	Excessive thirst	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Frequent urination	21	733	Frequent urination	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Vomiting	21	334	Vomiting	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Inappropriate urination	21	124	Inappropriate urination	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Urinary tract infection	21	2026	Urinary tract infection	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Renal failure	21	720	Renal failure	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Not defecating	21	3066	Not defecating	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005706	20260209	MSK	Cat	Euthanized	1	Reduced responses	21	1021	Reduced responses	1	Actual	False	False	true	1	1	Other	Animal Owner	20251014	20251014	Veterinarian	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001130	20260108	MSK	Cat	Outcome Unknown	1	Drooling	21	292	Drooling	1	Actual	False	False	true	1	1	Other	Other	20250107	20250107	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001130	20260108	MSK	Cat	Outcome Unknown	1	Pain NOS	21	1012	Pain NOS	1	Actual	False	False	true	1	1	Other	Other	20250107	20250107	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		E209228		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Staring	21	2635	Staring	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Hallucination	21	117	Hallucination	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Fear/fearful	21	3062	Fear/fearful	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-007459	20260220	MSK	Cat	Recovered/Normal	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Animal Owner	Animal Owner	20260219	20260219	Other	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/ NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005910	20260212	MSK	Cat	Ongoing	1	Febrile	21	1034	Febrile	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260212	20260212	Other	Topical	{'numerator': '0.50', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	785104447	2026-07	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005910	20260212	MSK	Cat	Ongoing	1	Pacing	21	2208	Pacing	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260212	20260212	Other	Topical	{'numerator': '0.50', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	785104447	2026-07	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005910	20260212	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260212	20260212	Other	Topical	{'numerator': '0.50', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	785104447	2026-07	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005855	20260211	MSK	Cat	Recovered/Normal	5	Behavioural disorder NOS	21	116	Behavioural disorder NOS	5	Actual	False	False		5	27	Other	Other	20200701	20220701	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-005855	20260211	MSK	Cat	Recovered/Normal	5	Aggression	21	113	Aggression	5	Actual	False	False		5	27	Other	Other	20200701	20220701	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011001	20260311	MSK	Cat	Outcome Unknown	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False		1	1	Other	Animal Owner	20260227	20260227	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011001	20260311	MSK	Cat	Outcome Unknown	1	Application site irritation	21	24	Application site irritation	1	Actual	False	False		1	1	Other	Animal Owner	20260227	20260227	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014107	20260324	MSK	Cat	Outcome Unknown	1	Head tilt - neurological disorder (see also Head tilt - ear disorder)	21	2523	Head tilt - neurological disorder (see also Head tilt - ear disorder)	1	Actual	False	False		1	1	Other	Other	20260324	20260324	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014107	20260324	MSK	Cat	Outcome Unknown	1	Ataxia	21	654	Ataxia	1	Actual	False	False		1	1	Other	Other	20260324	20260324	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006690	20260216	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other	Other								E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001962	20260121	MSK				Underfilling, Tubes	11	99031	Underfilling, Tubes			False	False				Other	Other								E210322	2026-12	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003473	20260127	MSK	Cat	Recovered/Normal	1	Open mouth breathing	21	1172	Open mouth breathing	1	Actual	False	False	true	1	1	Other	Veterinarian	20260108	20260108	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	20270131	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003473	20260127	MSK	Cat	Recovered/Normal	1	Respiratory distress	21	840	Respiratory distress	1	Actual	False	False	true	1	1	Other	Veterinarian	20260108	20260108	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	20270131	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003473	20260127	MSK	Cat	Recovered/Normal	1	Fever	21	1032	Fever	1	Actual	False	False	true	1	1	Other	Veterinarian	20260108	20260108	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	20270131	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003473	20260127	MSK	Cat	Recovered/Normal	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Other	Veterinarian	20260108	20260108	Other	Topical	{'numerator': '1', 'numerator_unit': 'dose', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	20270131	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014624	20260326	MSK	Cat	Recovered/Normal	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False	true	1	1	Other	Animal Owner	20260324	20260324	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027-02	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002588	20260114	MSK	Cat	Outcome Unknown	1	Impaired vocalisation	21	1935	Impaired vocalisation	1	Actual	False	False	false	1	1	Other	Veterinarian	20260105	20260105	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002588	20260114	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Other	Veterinarian	20260105	20260105	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002588	20260114	MSK	Cat	Outcome Unknown	1	Sedation prolonged	21	1903	Sedation prolonged	1	Actual	False	False	false	1	1	Other	Veterinarian	20260105	20260105	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E220855	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012097	20260316	MSK	Cat	Ongoing	1	Biting -aggression (see also Skin and appendages disorders)	21	112	Biting -aggression (see also Skin and appendages disorders)	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260313	20260313	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002357	20260120	MSK	Cat	Recovered/Normal	1	Eyes rolling back	21	2084	Eyes rolling back	1	Actual	False	False	true	1	1	Animal Owner	Other	20260116	20260116	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002357	20260120	MSK	Cat	Recovered/Normal	1	Hypotension	21	228	Hypotension	1	Actual	False	False	true	1	1	Animal Owner	Other	20260116	20260116	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002357	20260120	MSK	Cat	Recovered/Normal	1	Bradycardia	21	188	Bradycardia	1	Actual	False	False	true	1	1	Animal Owner	Other	20260116	20260116	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-002357	20260120	MSK	Cat	Recovered/Normal	1	Loss of consciousness	21	667	Loss of consciousness	1	Actual	False	False	true	1	1	Animal Owner	Other	20260116	20260116	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011402	20260311	MSK	Cat	Outcome Unknown	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False		1	1	Animal Owner	Other	20260310	20260310	Veterinarian	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011402	20260311	MSK	Cat	Outcome Unknown	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False		1	1	Animal Owner	Other	20260310	20260310	Veterinarian	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011402	20260311	MSK	Cat	Outcome Unknown	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False		1	1	Animal Owner	Other	20260310	20260310	Veterinarian	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-011402	20260311	MSK	Cat	Outcome Unknown	1	Restlessness	21	119	Restlessness	1	Actual	False	False		1	1	Animal Owner	Other	20260310	20260310	Veterinarian	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Agitation	21	121	Agitation	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Head bobbing	21	2022	Head bobbing	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Lack of coordination (see also Ear - vestibular disorder)	21	656	Lack of coordination (see also Ear - vestibular disorder)	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Impaired vision	21	407	Impaired vision	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006097	20260213	MSK	Cat	Ongoing	1	Not himself/herself	21	2753	Not himself/herself	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260211	20260211	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E230873	2027	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Restlessness	21	119	Restlessness	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Not drinking	21	541	Not drinking	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Pacing	21	2208	Pacing	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003636	20260123	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	false	1	1	Other	Animal Owner	20260122	20260122	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	2027-01	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Dermal nodule	21	2780	Dermal nodule	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Hiding	21	2207	Hiding	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Tongue disorder NOS	21	1845	Tongue disorder NOS	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Difficulty eating NOS	21	2847	Difficulty eating NOS	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Other abnormal test result NOS	21	1221	Other abnormal test result NOS	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Oral cavity disorder NOS	21	2229	Oral cavity disorder NOS	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Dysphagia	21	285	Dysphagia	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006674	20260213	MSK	Cat	Outcome Unknown	1	Hypertrophic concentric cardiomyopathy	21	2301	Hypertrophic concentric cardiomyopathy	1	Actual	False	False		1	1	Animal Owner	Veterinarian	20260124	20260124	Veterinarian	Transdermal	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014193	20260319	MSK	Cat	Recovered/Normal	4	Not sleeping	21	140	Not sleeping	4	Actual	False	False	false	4	4	Other	Veterinarian	20260101	20260101	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014193	20260319	MSK	Cat	Recovered/Normal	4	Hyperactivity	21	118	Hyperactivity	4	Actual	False	False	false	4	4	Other	Veterinarian	20260101	20260101	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014193	20260319	MSK	Cat	Recovered/Normal	4	Restlessness	21	119	Restlessness	4	Actual	False	False	false	4	4	Other	Veterinarian	20260101	20260101	Other	Topical		false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012217	20260313	MSK	Cat	Ongoing	1	Elevated temperature	21	1033	Elevated temperature	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012217	20260313	MSK	Cat	Ongoing	1	Decreased body temperature	21	1016	Decreased body temperature	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260313	20260313	Other	Topical	{'numerator': '0.40', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012231	20260316	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False		1	1	Veterinarian	Other	20260315	20260315	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012231	20260316	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False		1	1	Veterinarian	Other	20260315	20260315	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009576	20260303	MSK	Cat	Outcome Unknown	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False		1	1	Veterinarian		20260101	20260101	Unknown	Unknown				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009576	20260303	MSK	Cat	Outcome Unknown	1	Lethargy (see also Central nervous system depression in Neurological)	21	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	False	False		1	1	Veterinarian		20260101	20260101	Unknown	Unknown				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009576	20260303	MSK	Cat	Outcome Unknown	1	Arched back	21	2275	Arched back	1	Actual	False	False		1	1	Veterinarian		20260101	20260101	Unknown	Unknown				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009576	20260303	MSK	Cat	Outcome Unknown	1	Gait abnormality	21	1989	Gait abnormality	1	Actual	False	False		1	1	Veterinarian		20260101	20260101	Unknown	Unknown				ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008100	20260220	MSK	Cat	Outcome Unknown	1	Miosis	21	680	Miosis	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260218	20260218	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-008100	20260220	MSK	Cat	Outcome Unknown	1	Mydriasis	21	690	Mydriasis	1	Actual	False	False	false	1	1	Veterinarian	Animal Owner	20260218	20260218	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-012009	20260312	MSK	Cat	Outcome Unknown	4	Lack of efficacy - NOS	21	1039	Lack of efficacy - NOS	4	Estimated	False	False		4	4	Veterinarian	Other	20230101	20250101	Unknown	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001864	20260114	MSK	Cat	Outcome Unknown	2	Behavioural disorder NOS	21	116	Behavioural disorder NOS	2	Actual	False	False		2	2	Other	Other	20250101	20250101	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006830	20260210	MSK	Cat	Outcome Unknown	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260209	20260209	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006830	20260210	MSK	Cat	Outcome Unknown	1	Self trauma	21	125	Self trauma	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260209	20260209	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006830	20260210	MSK	Cat	Outcome Unknown	1	Elevated temperature	21	1033	Elevated temperature	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260209	20260209	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006830	20260210	MSK	Cat	Outcome Unknown	1	Mydriasis	21	690	Mydriasis	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260209	20260209	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-006830	20260210	MSK	Cat	Outcome Unknown	1	Wound	21	2593	Wound	1	Actual	False	False	true	1	1	Veterinarian	Animal Owner	20260209	20260209	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001804	20260116	MSK	Cat	Outcome Unknown	1	Hard stool	21	2677	Hard stool	1	Actual	False	False		1	1	Other	Veterinarian	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001804	20260116	MSK	Cat	Outcome Unknown	1	Not urinating	21	2520	Not urinating	1	Actual	False	False		1	1	Other	Veterinarian	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001804	20260116	MSK	Cat	Outcome Unknown	1	Urine abnormalities NOS	21	1959	Urine abnormalities NOS	1	Actual	False	False		1	1	Other	Veterinarian	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001804	20260116	MSK	Cat	Outcome Unknown	1	Unwell	21	2883	Unwell	1	Actual	False	False		1	1	Other	Veterinarian	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001804	20260116	MSK	Cat	Outcome Unknown	1	Abnormal radiograph finding	21	2070	Abnormal radiograph finding	1	Actual	False	False		1	1	Other	Veterinarian	20260114	20260114	Other	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001350	20260116	MSK	Cat	Outcome Unknown	1	Hyperthermia	21	1014	Hyperthermia	1	Actual	False	False	false	1	1	Other	Animal Owner	20260116	20260116	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-003167	20260123	MSK	Cat	Died	1	Death	21	984	Death	1	Actual	True	False		1	1	Veterinarian	Animal Owner	20260117	20260117	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	E249681	2027-05	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-014252	20260326	MSK				Product label issues	11	99857	Product label issues			False	False				Veterinarian	Other								NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-001040	20260109	MSK	Cat	Recovered/Normal	1	Seizure NOS	21	645	Seizure NOS	1	Actual	False	False	true	1	1	Other	Veterinarian	20260107	20260107	Animal Owner	Topical	{'numerator': '1', 'numerator_unit': 'mL', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	E226220	20270131	Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000912	20260112	MSK	Cat	Recovered/Normal	1	Application site alopecia	21	2	Application site alopecia	1	Actual	False	False	true	1	1	Other	Animal Owner	20251111	20251111	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000912	20260112	MSK	Cat	Recovered/Normal	1	Application site pruritus	21	25	Application site pruritus	1	Actual	False	False	true	1	1	Other	Animal Owner	20251111	20251111	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-000912	20260112	MSK	Cat	Recovered/Normal	1	Application site scab	21	15	Application site scab	1	Actual	False	False	true	1	1	Other	Animal Owner	20251111	20251111	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}			ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Hallucination	21	117	Hallucination	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Easily startled	21	3061	Easily startled	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Staring	21	2635	Staring	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Not drinking	21	541	Not drinking	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Behavioural disorder NOS	21	116	Behavioural disorder NOS	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Not defecating	21	3066	Not defecating	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Dysphoria	21	2531	Dysphoria	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Diarrhoea	21	302	Diarrhoea	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009693	20260303	MSK	Cat	Ongoing	1	Increased urine volume	21	2773	Increased urine volume	1	Actual	False	False	false	1	1	Animal Owner	Veterinarian	20260302	20260302	Veterinarian	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Balance impaired	21	1341	Balance impaired	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Not drinking	21	541	Not drinking	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Not eating	21	1207	Not eating	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Not sleeping	21	140	Not sleeping	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Not urinating	21	2520	Not urinating	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Pacing	21	2208	Pacing	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Not defecating	21	3066	Not defecating	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Hyperactivity	21	118	Hyperactivity	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Dilated pupils	21	1414	Dilated pupils	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Nervous	21	3063	Nervous	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-013528	20260323	MSK	Cat	Ongoing	1	Balance problem	21	372	Balance problem	1	Actual	False	False	true	1	1	Animal Owner	Other	20260319	20260319	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Fever	21	1032	Fever	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Not urinating	21	2520	Not urinating	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Elevated aspartate aminotransferase (AST)	21	2049	Elevated aspartate aminotransferase (AST)	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Decreased blood urea nitrogen (BUN) or creatinine	21	2702	Decreased blood urea nitrogen (BUN) or creatinine	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Low creatinine	21	2701	Low creatinine	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Hypocalcaemia	21	2685	Hypocalcaemia	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}
USA-USFDACVM-2026-US-009570	20260226	MSK	Cat	Recovered/Normal	1	Hypoproteinaemia	21	1976	Hypoproteinaemia	1	Actual	False	False	true	1	1	Other	Veterinarian	20260225	20260225	Other	Topical	{'numerator': '1', 'numerator_unit': 'tube', 'denominator': '1', 'denominator_unit': 'Animal'}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{"name": "MSK", "registration_number": "USA-USFDACVM-N141547"}