Data 2025Q4

unique_aer_id_number	receive_date	drug	animal_species	reaction	reaction_outcome	veddra_version	veddra_term_code	veddra_term_name	reaction_animals_affected	reaction_accuracy	receiver	treated_for_ae	number_of_animals_affected	number_of_animals_treated	primary_reporter	secondary_reporter	first_exposure_date	last_exposure_date	administered_by	route	dose	used_according_to_label	off_label_use	lot_number	lot_expiration	dosage_form	atc_vet_code	active_ingredients	manufacturer
USA-USFDACVM-2025-US-028909	20250527	MSK	Cat	Application site infection		18	2005	Application site infection	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250505	20250505	Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	20260430	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028909	20250527	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250505	20250505	Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	20260430	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Pale mucous membrane		18	222	Pale mucous membrane	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Hypothermia		18	1015	Hypothermia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Hypersalivation		18	293	Hypersalivation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Open mouth breathing		18	1172	Open mouth breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Vomiting bile		18	2758	Vomiting bile	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027080	20250516	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Hallucination		18	117	Hallucination	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Rubbing		18	2496	Rubbing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Crying		18	130	Crying	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Nystagmus		18	691	Nystagmus	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018565	20250410	MSK	Cat	Application site hair change		18	1878	Application site hair change	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250408	20250408	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017494	20250408	MSK	Cat	Application site reddening		18	1332	Application site reddening	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250404	20250404	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017494	20250408	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250404	20250404	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017494	20250408	MSK	Cat	Application site itching		18	23	Application site itching	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250404	20250404	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Haemorrhage NOS		18	177	Haemorrhage NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Unable to jump		18	2394	Unable to jump	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018075	20250414	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027415	20250521	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Other	20250520	20250520	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027415	20250521	MSK	Cat	Hyperthermia		18	1014	Hyperthermia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Other	20250520	20250520	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027415	20250521	MSK	Cat	Mydriasis		18	690	Mydriasis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Other	20250520	20250520	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025857	20250515	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250410	20250410	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E175476	20260430	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018081	20250414	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018081	20250414	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018081	20250414	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018081	20250414	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018081	20250414	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250325	20250325	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	20260531	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Heavy breathing		18	2776	Heavy breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Adipsia		18	542	Adipsia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Ataxia		18	654	Ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Glazed eye		18	1211	Glazed eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Hyperexcitation		18	122	Hyperexcitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035200	20250620	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Hypercalcaemia		18	553	Hypercalcaemia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Sedation		18	111	Sedation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Proteinuria		18	1961	Proteinuria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Head tilt – neurological disorder (see also Head tilt – ear disorder)		18	2523	Head tilt – neurological disorder (see also Head tilt – ear disorder)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Head pressing		18	636	Head pressing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020237	20250425	MSK	Cat	Tiredness		18	1844	Tiredness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033395	20250607	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other		20250604	20250604	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033395	20250607	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other		20250604	20250604	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033395	20250607	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other		20250604	20250604	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024884	20250501	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Other	20250401	20250401	Unknown	Topical	{“numerator”: “8”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “Animal”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024884	20250501	MSK	Cat	Application site scab		18	15	Application site scab	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Other	20250401	20250401	Unknown	Topical	{“numerator”: “8”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “Animal”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020260	20250424	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250422	20250422	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020260	20250424	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250422	20250422	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023992	20250508	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	10	Actual	Food and Drug Administration Center for Veterinary Medicine		10	10	Veterinarian		20250101	20250101	Veterinarian	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028274	20250521	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other		20250519	20250519	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028274	20250521	MSK	Cat	Bumping into walls		18	2403	Bumping into walls	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other		20250519	20250519	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026502	20250516	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026502	20250516	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026502	20250516	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028278	20250521	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250519	20250519	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028278	20250521	MSK	Cat	Bumping into walls		18	2403	Bumping into walls	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250519	20250519	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Staring		18	2635	Staring	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032616	20250612	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Animal Owner		20250611	20250611	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018858	20250418	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018858	20250418	MSK	Cat	Irritability		18	1559	Irritability	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018858	20250418	MSK	Cat	Ataxia		18	654	Ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018858	20250418	MSK	Cat	Diarrhoea		18	302	Diarrhoea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018858	20250418	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Decreased drinking		18	2500	Decreased drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020357	20250423	MSK	Cat	Sleep disturbance NOS		18	141	Sleep disturbance NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250421	20250421	Veterinarian	Topical		false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022368	20250501	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022368	20250501	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022368	20250501	MSK	Cat	Pacing		18	2208	Pacing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018872	20250416	MSK	Cat	Application site lesion		18	14	Application site lesion	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250401	20250401	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	20260330	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018872	20250416	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250401	20250401	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	20260330	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Staring		18	2635	Staring	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Hypersalivation		18	293	Hypersalivation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023947	20250502	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017736	20250407	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017736	20250407	MSK	Cat	Breathing difficulty		18	1170	Breathing difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017736	20250407	MSK	Cat	Recovery prolonged		18	1904	Recovery prolonged	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017876	20250404	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017876	20250404	MSK	Cat	Diabetic ketoacidosis		18	2053	Diabetic ketoacidosis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017876	20250404	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017876	20250404	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022373	20250501	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022373	20250501	MSK	Cat	Pacing		18	2208	Pacing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022373	20250501	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20241201	20241201	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Application site crust		18	16	Application site crust	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Application site pruritus		18	25	Application site pruritus	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Haemorrhage NOS		18	177	Haemorrhage NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Ear discharge		18	349	Ear discharge	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Itching		18	958	Itching	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Scratching		18	959	Scratching	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Pruritus		18	960	Pruritus	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Skin ulcer		18	1194	Skin ulcer	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Local swelling (not application site)		18	1580	Local swelling (not application site)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Localised hair loss		18	1581	Localised hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Licking at application site		18	1973	Licking at application site	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025010	20250509	MSK	Cat	Skin scab		18	2179	Skin scab	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250429	20250429	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018227	20250415	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250415	20250415	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021163	20250425	MSK	Cat	Sedation		18	111	Sedation	5	Actual	Food and Drug Administration Center for Veterinary Medicine		5	5	Veterinarian	Animal Owner	20250101	20250101	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033842	20250618	MSK	Cat	Facial swelling (see also Skin)		18	517	Facial swelling (see also Skin)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250618	20250618	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027077	20250520	MSK		Underfilling, Tubes		10	99031	Underfilling, Tubes			Food and Drug Administration Center for Veterinary Medicine				Other									E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018862	20250417	MSK	Cat	Falling		18	651	Falling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250416	20250416	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018862	20250417	MSK	Cat	Limping		18	1990	Limping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250416	20250416	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018862	20250417	MSK	Cat	Anuria		18	712	Anuria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250416	20250416	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018862	20250417	MSK	Cat	Urinary tract obstruction/blockage		18	2874	Urinary tract obstruction/blockage	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250416	20250416	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Hypersalivation		18	293	Hypersalivation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Administration error NOS		18	3035	Administration error NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Mydriasis		18	690	Mydriasis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Dazed		18	3109	Dazed	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Diarrhoea		18	302	Diarrhoea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023351	20250425	MSK	Cat	Digestive tract disorder NOS		18	305	Digestive tract disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250425	20250425	Other	Oral	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	E169404	20260420	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030410	20250527	MSK	Cat	Respiratory signs		18	1181	Respiratory signs	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250527	20250527	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E178036		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030410	20250527	MSK	Cat	Increased respiratory rate		18	856	Increased respiratory rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250527	20250527	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E178036		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020124	20250421	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250414	20250414	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020124	20250421	MSK	Cat	Application site lesion		18	14	Application site lesion	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250414	20250414	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020124	20250421	MSK	Cat	Application site reddening		18	1332	Application site reddening	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250414	20250414	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018226	20250409	MSK	Cat	Unclassifiable adverse event		18	2190	Unclassifiable adverse event	1	Actual	Food and Drug Administration Center for Veterinary Medicine		2	2	Other		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025865	20250515	MSK	Cat	Uncomfortable		18	2499	Uncomfortable	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250515	20250515	Other	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025865	20250515	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250515	20250515	Other	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025865	20250515	MSK	Cat	Panting		18	855	Panting	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250515	20250515	Other	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025865	20250515	MSK	Cat	Pacing		18	2208	Pacing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250515	20250515	Other	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030734	20250605	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030734	20250605	MSK	Cat	Application site lump		18	21	Application site lump	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017424	20250407	MSK	Cat	Scratching		18	959	Scratching	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250321	20250321	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017424	20250407	MSK	Cat	Rubbing		18	2496	Rubbing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250321	20250321	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017424	20250407	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250321	20250321	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017424	20250407	MSK	Cat	Application site itching		18	23	Application site itching	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250321	20250321	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017160	20250403	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250325	20250325	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017160	20250403	MSK	Cat	Anuria		18	712	Anuria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250325	20250325	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017160	20250403	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250325	20250325	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017160	20250403	MSK	Cat	Bloody diarrhoea		18	315	Bloody diarrhoea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250325	20250325	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017160	20250403	MSK	Cat	Adipsia		18	542	Adipsia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250325	20250325	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E164780	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020121	20250422	MSK	Cat	Hiding		18	2207	Hiding	50	Estimated	Food and Drug Administration Center for Veterinary Medicine		50	50	Veterinarian	Other	20250101	20250101	Veterinarian	Topical				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020121	20250422	MSK	Cat	Decreased appetite		18	998	Decreased appetite	50	Estimated	Food and Drug Administration Center for Veterinary Medicine		50	50	Veterinarian	Other	20250101	20250101	Veterinarian	Topical				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020121	20250422	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	50	Estimated	Food and Drug Administration Center for Veterinary Medicine		50	50	Veterinarian	Other	20250101	20250101	Veterinarian	Topical				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Nervous		18	3063	Nervous	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Hypersalivation		18	293	Hypersalivation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Pain NOS		18	1012	Pain NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Tachycardia		18	192	Tachycardia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Urinary bladder disorder NOS		18	732	Urinary bladder disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Inappropriate defecation		18	123	Inappropriate defecation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-034971	20250618	MSK	Cat	Inappropriate urination		18	124	Inappropriate urination	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250617	20250617	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028510	20250523	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250519	20250519	Animal Owner	Topical		false	Indication Off-Label	E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028510	20250523	MSK	Cat	Defect Unknown/Not Specified		10	99009	Defect Unknown/Not Specified			Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250519	20250519	Animal Owner	Topical		false	Indication Off-Label	E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025543	20250507	MSK	Cat	Sedation		18	111	Sedation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250420	20250505	Veterinarian	Topical		false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025543	20250507	MSK	Cat	Delayed healing		18	2081	Delayed healing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250420	20250505	Veterinarian	Topical		false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017846	20250408	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250402	20250402	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023394	20250501	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine		2	2	Veterinarian		20250101	20250101	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023394	20250501	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		2	2	Veterinarian		20250101	20250101	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033398	20250610	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250521	20250521	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030012	20250529	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250522	20250522	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030012	20250529	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250522	20250522	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030012	20250529	MSK	Cat	Pain NOS		18	1012	Pain NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250522	20250522	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030012	20250529	MSK	Cat	Lack of efficacy – NOS		18	1039	Lack of efficacy – NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250522	20250522	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019089	20250421	MSK	Cat	Twitching		18	686	Twitching	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250421	20250421	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019089	20250421	MSK	Cat	Trembling		18	687	Trembling	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250421	20250421	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019089	20250421	MSK	Cat	Palpebral disorder NOS		18	426	Palpebral disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250421	20250421	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019089	20250421	MSK	Cat	Sedation		18	111	Sedation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250421	20250421	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019089	20250421	MSK	Cat	Recovery prolonged		18	1904	Recovery prolonged	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250421	20250421	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018871	20250418	MSK	Cat	Hypoglycaemia		18	1947	Hypoglycaemia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018871	20250418	MSK	Cat	Seizure NOS		18	645	Seizure NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018871	20250418	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018871	20250418	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018871	20250418	MSK	Cat	Hyperaesthesia		18	706	Hyperaesthesia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018660	20250416	MSK	Cat	Skin warmth		18	2398	Skin warmth	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250415	20250415	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018660	20250416	MSK	Cat	Facial swelling (see also Skin)		18	517	Facial swelling (see also Skin)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250415	20250415	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018660	20250416	MSK	Cat	Hyperthermia		18	1014	Hyperthermia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250415	20250415	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026894	20250509	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026894	20250509	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026894	20250509	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031540	20250606	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250604	20250604	Unknown	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031540	20250606	MSK	Cat	Walking difficulty		18	1902	Walking difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250604	20250604	Unknown	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031540	20250606	MSK	Cat	Nystagmus		18	691	Nystagmus	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250604	20250604	Unknown	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031540	20250606	MSK	Cat	Head tilt – neurological disorder (see also Head tilt – ear disorder)		18	2523	Head tilt – neurological disorder (see also Head tilt – ear disorder)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250604	20250604	Unknown	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030478	20250602	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250531	20250531	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030478	20250602	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250531	20250531	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030478	20250602	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250531	20250531	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022367	20250501	MSK	Cat	Application site pruritus		18	25	Application site pruritus	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022367	20250501	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022367	20250501	MSK	Cat	Application site erythema		18	5	Application site erythema	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250424	20250424	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024991	20250513	MSK		Underfilling, Tubes		10	99031	Underfilling, Tubes			Food and Drug Administration Center for Veterinary Medicine				Other									E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031625	20250605	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250604	20250604	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031625	20250605	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250604	20250604	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031625	20250605	MSK	Cat	Underdose		18	3037	Underdose	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250604	20250604	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023344	20250423	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023344	20250423	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023344	20250423	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023344	20250423	MSK	Cat	Dehydration		18	1208	Dehydration	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023344	20250423	MSK	Cat	Nausea		18	1638	Nausea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024470	20250507	MSK	Cat	Aggression		18	113	Aggression	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Other	Other	20250101	20250101	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024470	20250507	MSK	Cat	Biting -aggression (see also Skin and appendages disorders)		18	112	Biting -aggression (see also Skin and appendages disorders)	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Other	Other	20250101	20250101	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025023	20250508	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025023	20250508	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025023	20250508	MSK	Cat	Drooling		18	292	Drooling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025023	20250508	MSK	Cat	Fever		18	1032	Fever	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025023	20250508	MSK	Cat	Dehydration		18	1208	Dehydration	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Head down		18	2397	Head down	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Dazed		18	3109	Dazed	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Lateral recumbency		18	1135	Lateral recumbency	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Icterus		18	499	Icterus	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Local swelling (not application site)		18	1580	Local swelling (not application site)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Abnormal radiograph finding		18	2070	Abnormal radiograph finding	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Abnormal breathing		18	837	Abnormal breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Increased respiratory rate		18	856	Increased respiratory rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Open mouth breathing		18	1172	Open mouth breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Miosis		18	680	Miosis	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Neurological signs NOS		18	630	Neurological signs NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Obtunded		18	3108	Obtunded	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Neutropenia		18	167	Neutropenia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Hypoglycaemia		18	1947	Hypoglycaemia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	HYPERBILIRUBINEMIA		9	99201	HYPERBILIRUBINEMIA	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Elevated blood urea nitrogen (BUN)		18	2047	Elevated blood urea nitrogen (BUN)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Elevated creatinine		18	2048	Elevated creatinine	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Agonal breathing		18	2777	Agonal breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Bradycardia		18	188	Bradycardia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-037165	20250603	MSK	Cat	Respiratory arrest		18	831	Respiratory arrest	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250515	20250515	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E164780	20260331	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024962	20250508	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Other	20241205	20241205	Veterinarian	Topical						Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024962	20250508	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Other	20241205	20241205	Veterinarian	Topical						Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024962	20250508	MSK	Cat	Panting		18	855	Panting	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Other	20241205	20241205	Veterinarian	Topical						Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024962	20250508	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Other	20241205	20241205	Veterinarian	Topical						Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Shaking		18	2002	Shaking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Anuria		18	712	Anuria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Star-gazing		18	2246	Star-gazing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Constipation		18	267	Constipation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Eye disorder NOS (for Photophobia see neurological)		18	452	Eye disorder NOS (for Photophobia see neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Emesis		18	335	Emesis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Other abnormal test result NOS		18	1221	Other abnormal test result NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033858	20250617	MSK	Cat	Not himself/herself		18	2753	Not himself/herself	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250614	20250614	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020027	20250422	MSK	Cat	Falling		18	651	Falling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Other	20250421	20250421	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020027	20250422	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Other	20250421	20250421	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020027	20250422	MSK	Cat	Malaise		18	1027	Malaise	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Other	20250421	20250421	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020027	20250422	MSK	Cat	Underdose		18	3037	Underdose	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Other	20250421	20250421	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033387	20250610	MSK	Cat	Mydriasis		18	690	Mydriasis	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250609	20250609	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033387	20250610	MSK	Cat	Hyperaesthesia		18	706	Hyperaesthesia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250609	20250609	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033794	20250610	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	3	Estimated	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian	Animal Owner	20250101	20250101	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033846	20250618	MSK	Cat	Breathing difficulty		18	1170	Breathing difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033846	20250618	MSK	Cat	Localised oedema (not application site)		18	1586	Localised oedema (not application site)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250617	20250617	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Ileus		18	1086	Ileus	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Inappetence		18	999	Inappetence	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Not defecating		18	3066	Not defecating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Distension of abdomen		18	312	Distension of abdomen	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Abnormal radiograph finding		18	2070	Abnormal radiograph finding	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Bloated		18	1349	Bloated	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027669	20250509	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250505	20250505	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023157	20250501	MSK	Cat	Not defecating		18	3066	Not defecating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250428	20250428	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023157	20250501	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250428	20250428	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023157	20250501	MSK	Cat	Not urinating		18	2520	Not urinating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250428	20250428	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Weight loss		18	1043	Weight loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Dull		18	2274	Dull	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Agonal breathing		18	2777	Agonal breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Death by euthanasia		18	981	Death by euthanasia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Weak pulse		18	2187	Weak pulse	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032194	20250609	MSK	Cat	Unresponsive to stimuli		18	2247	Unresponsive to stimuli	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}			E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Disorientation		18	660	Disorientation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Dehydration		18	1208	Dehydration	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Anaemia NOS		18	142	Anaemia NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Elevated symmetrical dimethylarginine (SDMA)		18	2583	Elevated symmetrical dimethylarginine (SDMA)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Abnormal menace reflex test		18	1096	Abnormal menace reflex test	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Rale		18	852	Rale	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033833	20250608	MSK	Cat	Abnormal radiograph finding		18	2070	Abnormal radiograph finding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250605	20250605	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031635	20250606	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031635	20250606	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031635	20250606	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031635	20250606	MSK	Cat	Reduced food intake		18	2783	Reduced food intake	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250603	20250603	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Hypotension		18	228	Hypotension	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Ataxia		18	654	Ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Unable to walk		18	3017	Unable to walk	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Unable to stand		18	653	Unable to stand	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Hind limb ataxia		18	1134	Hind limb ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Crying		18	130	Crying	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Warm feeling to the touch		18	2742	Warm feeling to the touch	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Neurological disorder NOS		18	2728	Neurological disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Quiet		18	2645	Quiet	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Hypokalaemia		18	2418	Hypokalaemia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Agonal breathing		18	2777	Agonal breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Obtunded		18	3108	Obtunded	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Slow heart rate		18	190	Slow heart rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Cardiomyopathy		18	205	Cardiomyopathy	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Heart murmur		18	213	Heart murmur	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Brain disorder NOS		18	1356	Brain disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Respiratory arrest		18	831	Respiratory arrest	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Unclassifiable adverse event		18	2190	Unclassifiable adverse event	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Pupil disorder		18	432	Pupil disorder	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Abnormal menace reflex test		18	1096	Abnormal menace reflex test	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Paraplegia		18	692	Paraplegia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030209	20250529	MSK	Cat	Paraparesis		18	699	Paraparesis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250527	20250527	Unknown	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033847	20250619	MSK		Defect Unknown/Not Specified		10	99009	Defect Unknown/Not Specified			Food and Drug Administration Center for Veterinary Medicine				Other									NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020014	20250421	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250407	20250407	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Overdosed	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020014	20250421	MSK	Cat	Application site scratching		18	26	Application site scratching	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250407	20250407	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Overdosed	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020014	20250421	MSK	Cat	Tooth loss		18	2448	Tooth loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Veterinarian	20250407	20250407	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Overdosed	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025709	20250515	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Veterinarian	Topical	{“numerator”: “0.50”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025709	20250515	MSK	Cat	Application site burn		18	2063	Application site burn	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250329	20250329	Veterinarian	Topical	{“numerator”: “0.50”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018469	20250407	MSK	Cat	Inappetence		18	999	Inappetence	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	2	2	Veterinarian	Animal Owner	20250315	20250315	Other	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Abnormal radiograph finding		18	2070	Abnormal radiograph finding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Neurological symptoms NOS		18	1648	Neurological symptoms NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Oral bleeding		18	297	Oral bleeding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Death by euthanasia		18	981	Death by euthanasia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Ataxia		18	654	Ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Swollen gum		18	1815	Swollen gum	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Weakness		18	1023	Weakness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Low platelet count		18	161	Low platelet count	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Tachycardia		18	192	Tachycardia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Decreased packed cell volume (PCV)		18	2215	Decreased packed cell volume (PCV)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Tachypnoea		18	854	Tachypnoea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Bradycardia		18	188	Bradycardia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Respiratory signs		18	1181	Respiratory signs	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Coagulopathy		18	1057	Coagulopathy	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-026903	20250506	MSK	Cat	Blood loss NOS		18	1352	Blood loss NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250225	20250225	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-016503	20250402	MSK	Cat	Elevated temperature		18	1033	Elevated temperature	20	Actual	Food and Drug Administration Center for Veterinary Medicine		20	20	Other		20250101	20250101	Unknown	Unknown				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035290	20250619	MSK	Cat	Gagging		18	344	Gagging	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Rolling		18	2391	Rolling	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017679	20250410	MSK	Cat	Sleepiness – systemic disorder		18	2529	Sleepiness – systemic disorder	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Veterinarian	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019841	20250411	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250328	20250328	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Sedation		18	111	Sedation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Tremor		18	1852	Tremor	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Inappropriate urination		18	124	Inappropriate urination	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Walking difficulty		18	1902	Walking difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Not drinking		18	541	Not drinking	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Unable to stand		18	653	Unable to stand	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Wobbliness		18	2871	Wobbliness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Hypersensitivity NOS		18	514	Hypersensitivity NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Sleepiness – systemic disorder		18	2529	Sleepiness – systemic disorder	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Mental impairment NOS		18	1612	Mental impairment NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Pupil disorder		18	432	Pupil disorder	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Ataxia		18	654	Ataxia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033524	20250616	MSK	Cat	Weight loss		18	1043	Weight loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250612	20250612	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186725	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018882	20250418	MSK	Cat	Unclassifiable adverse event		18	2190	Unclassifiable adverse event	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Other		20250101	20250101	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Excessive thirst		18	544	Excessive thirst	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Hind limb paresis		18	1153	Hind limb paresis	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Stupor		18	1019	Stupor	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Unresponsive to stimuli		18	2247	Unresponsive to stimuli	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Anxiety		18	115	Anxiety	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Fit		18	643	Fit	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Cold feeling to the touch		18	2741	Cold feeling to the touch	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Walking difficulty		18	1902	Walking difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Falling		18	651	Falling	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Seizure NOS		18	645	Seizure NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Convulsion		18	642	Convulsion	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Loss of consciousness		18	667	Loss of consciousness	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Breathing difficulty		18	1170	Breathing difficulty	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Slow heart rate		18	190	Slow heart rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Decreased respiratory rate		18	834	Decreased respiratory rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Excitation		18	120	Excitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Underdose		18	3037	Underdose	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Hind limb paralysis		18	2025	Hind limb paralysis	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-030736	20250527	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250523	20250523	Veterinarian	Transdermal	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Indication Off-Label	E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Sleep disturbance NOS		18	141	Sleep disturbance NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018687	20250417	MSK	Cat	Decreased bowel movements		18	1939	Decreased bowel movements	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner	Veterinarian	20250414	20250414	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Red eye		18	1721	Red eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Swollen eye		18	1810	Swollen eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Administration error NOS		18	3035	Administration error NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Eye irritation		18	453	Eye irritation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Eye disorder NOS (for Photophobia see neurological)		18	452	Eye disorder NOS (for Photophobia see neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033288	20250611	MSK	Cat	Chemosis		18	1107	Chemosis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250609	20250609	Other	Intraocular	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Route Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022325	20250429	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250410	20250410	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-022325	20250429	MSK	Cat	Weight loss		18	1043	Weight loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250410	20250410	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019075	20250422	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250402	20250402	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E202915		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019075	20250422	MSK	Cat	Application site scratching		18	26	Application site scratching	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250402	20250402	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E202915		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Low blood pressure		18	229	Low blood pressure	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Increased appetite		18	1530	Increased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019964	20250418	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250417	20250417	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E169404	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024995	20250512	MSK	Cat	Reddening of the skin		18	946	Reddening of the skin	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024995	20250512	MSK	Cat	Wound		18	2593	Wound	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024995	20250512	MSK	Cat	Skin lesion NOS		18	966	Skin lesion NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024995	20250512	MSK	Cat	Itching		18	958	Itching	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian		20250505	20250505	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018487	20250401	MSK	Cat	Underdose		18	3037	Underdose	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250401	20250401	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018487	20250401	MSK	Cat	Elevated temperature		18	1033	Elevated temperature	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250401	20250401	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018487	20250401	MSK	Cat	Anxiety		18	115	Anxiety	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250401	20250401	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018487	20250401	MSK	Cat	Mewing		18	131	Mewing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250401	20250401	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018487	20250401	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250401	20250401	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed, Treatment regimen Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Confusion		18	659	Confusion	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Lying down		18	2743	Lying down	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Unconscious		18	1857	Unconscious	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Not defecating		18	3066	Not defecating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023347	20250423	MSK	Cat	Not urinating		18	2520	Not urinating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250417		Other	Transdermal	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017238	20250407	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017238	20250407	MSK	Cat	Mental confusion		18	1609	Mental confusion	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017238	20250407	MSK	Cat	Hallucination		18	117	Hallucination	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017238	20250407	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017238	20250407	MSK	Cat	Neurological disorder NOS		18	2728	Neurological disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Veterinarian	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017366	20250404	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian		20250306	20250306	Unknown	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}			E167322	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Not sleeping		18	140	Not sleeping	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Disoriented state		18	1418	Disoriented state	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Staring		18	2635	Staring	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018135	20250408	MSK	Cat	Not defecating		18	3066	Not defecating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250402	20250402	Other	Topical				NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033390	20250611	MSK	Cat	Swelling around eye		18	461	Swelling around eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250609	20250609	Other	Intraocular		false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033390	20250611	MSK	Cat	Closed eyelid		18	1233	Closed eyelid	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250609	20250609	Other	Intraocular		false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033390	20250611	MSK	Cat	Red eye		18	1721	Red eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250609	20250609	Other	Intraocular		false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033390	20250611	MSK	Cat	Swollen eye		18	1810	Swollen eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner		20250609	20250609	Other	Intraocular		false	Route Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028958	20250529	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250528	20250528	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028958	20250529	MSK	Cat	Growling		18	2755	Growling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250528	20250528	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028958	20250529	MSK	Cat	Circling – behavioural disorder (see also Neurological disorders)		18	2611	Circling – behavioural disorder (see also Neurological disorders)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250528	20250528	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028958	20250529	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250528	20250528	Other	Topical	{“numerator”: “1”, “numerator_unit”: “dose”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	20260630	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019855	20250418	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019855	20250418	MSK	Cat	Distress		18	114	Distress	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019855	20250418	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019855	20250418	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019855	20250418	MSK	Cat	Unwell		18	2883	Unwell	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023516	20250501	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250430	20250430	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E202915	20260930	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023516	20250501	MSK	Cat	Hyperactivity		18	118	Hyperactivity	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250430	20250430	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Underdosed	E202915	20260930	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018234	20250414	MSK	Cat	Hyperthermia		18	1014	Hyperthermia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250413	20250413	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018234	20250414	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250413	20250413	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018234	20250414	MSK	Cat	Open mouth breathing		18	1172	Open mouth breathing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250413	20250413	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Adipsia		18	542	Adipsia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Lateral recumbency		18	1135	Lateral recumbency	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Urinary tract obstruction/blockage		18	2874	Urinary tract obstruction/blockage	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Inappropriate urination		18	124	Inappropriate urination	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Glazed eye		18	1211	Glazed eye	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Hyperglycaemia		18	1946	Hyperglycaemia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Elevated renal parameters		18	1992	Elevated renal parameters	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-035176	20250620	MSK	Cat	Hyperexcitation		18	122	Hyperexcitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other		20250612	20250616	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E182577	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Rolling		18	2391	Rolling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Pacing		18	2208	Pacing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Rubbing		18	2496	Rubbing	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Diarrhoea		18	302	Diarrhoea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Sleepiness – systemic disorder		18	2529	Sleepiness – systemic disorder	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Distress		18	114	Distress	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Appetite disorder NOS		18	1323	Appetite disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Weight loss		18	1043	Weight loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018667	20250414	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250331	20250331	Veterinarian	Transdermal	{“numerator”: “20”, “numerator_unit”: “Milligram”, “denominator”: “1”, “denominator_unit”: “mL”}			UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025885	20250512	MSK	Cat	Hissing		18	2754	Hissing	2	Actual	Food and Drug Administration Center for Veterinary Medicine		2	2	Other	Other	20250213	20250213	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Dysphoria		18	2531	Dysphoria	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Sedation		18	111	Sedation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Hypersalivation		18	293	Hypersalivation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Fever		18	1032	Fever	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Staring		18	2635	Staring	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Tachycardia		18	192	Tachycardia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Lateral recumbency		18	1135	Lateral recumbency	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025229	20250508	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250508	20250508	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E109292	2025-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Panting		18	855	Panting	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Vocalisation		18	129	Vocalisation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Loss of bowel control		18	1070	Loss of bowel control	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Bladder incontinence		18	1346	Bladder incontinence	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Unable to walk		18	3017	Unable to walk	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Cold feeling to the touch		18	2741	Cold feeling to the touch	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-021166	20250424	MSK	Cat	Agitation		18	121	Agitation	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250423	20250423	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Not eating		18	1207	Not eating	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Dysphoria		18	2531	Dysphoria	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Distress		18	114	Distress	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Agitation		18	121	Agitation	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-019970	20250418	MSK	Cat	Unwell		18	2883	Unwell	3	Actual	Food and Drug Administration Center for Veterinary Medicine		3	3	Veterinarian		20250101	20250101	Unknown	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-032192	20250613	MSK		Underfilling, Tubes		10	99031	Underfilling, Tubes			Food and Drug Administration Center for Veterinary Medicine				Other									E175476	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024029	20250430	MSK	Cat	Vomiting		18	334	Vomiting	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250429	20250429	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024029	20250430	MSK	Cat	Subdued		18	2646	Subdued	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250429	20250429	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024029	20250430	MSK	Cat	Quiet		18	2645	Quiet	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250429	20250429	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-024029	20250430	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250429	20250429	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	E178036	2026-05	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018078	20250409	MSK	Cat	Stiffness NOS		18	1794	Stiffness NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018078	20250409	MSK	Cat	Respiratory distress		18	840	Respiratory distress	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018078	20250409	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Other	Animal Owner	20250408	20250408	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028922	20250516	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250514	20250514	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028922	20250516	MSK	Cat	Nausea		18	1638	Nausea	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250514	20250514	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-028922	20250516	MSK	Cat	Inappetence		18	999	Inappetence	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Veterinarian	Animal Owner	20250514	20250514	Unknown	Unknown				UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033864	20250613	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250501	20250501	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033864	20250613	MSK	Cat	Renal disorder NOS		18	719	Renal disorder NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250501	20250501	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033864	20250613	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250501	20250501	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033864	20250613	MSK	Cat	Decreased appetite		18	998	Decreased appetite	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250501	20250501	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033864	20250613	MSK	Cat	Anorexia		18	996	Anorexia	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Animal Owner		20250501	20250501	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-023869	20250505	MSK	Cat	Enlarged lymph node (localised)		18	2405	Enlarged lymph node (localised)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250501	20250501	Other	Transdermal				E166343	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020254	20250422	MSK	Cat	Cyanotic mucous membranes		18	2988	Cyanotic mucous membranes	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250422	20250422	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E080653	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020254	20250422	MSK	Cat	Cardiac arrest		18	195	Cardiac arrest	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250422	20250422	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E080653	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020254	20250422	MSK	Cat	Death by euthanasia		18	981	Death by euthanasia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250422	20250422	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E080653	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020254	20250422	MSK	Cat	Increased heart rate		18	193	Increased heart rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Other	Animal Owner	20250422	20250422	Other	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E080653	2026-03	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-018957	20250416	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Veterinarian	Animal Owner	20250410	20250410	Veterinarian	Topical	{“numerator”: “0.40”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E202915	20260930	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Injection site lump		18	92	Injection site lump	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Sarcoma NOS		18	2973	Sarcoma NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Injection site swelling		18	91	Injection site swelling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Spindle cell tumour		18	924	Spindle cell tumour	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Abnormal cytology		18	2588	Abnormal cytology	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Monocytosis		18	2420	Monocytosis	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Elevated red cell distribution width (RDW)		18	2857	Elevated red cell distribution width (RDW)	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Mass NOS		18	2886	Mass NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Aggression		18	113	Aggression	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Other abnormal test result NOS		18	1221	Other abnormal test result NOS	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025872	20250415	MSK	Cat	Fibrosarcoma		18	2918	Fibrosarcoma	1	Actual	Food and Drug Administration Center for Veterinary Medicine	true	1	1	Animal Owner	Veterinarian	20250502	20250502	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Treatment regimen Off-Label	UNKNOWN		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-031812	20250610	MSK	Cat	Application site alopecia		18	2	Application site alopecia	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other		20250513	20250513	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E202915	2026-09	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027665	20250522	MSK	Cat	Behavioural disorder NOS		18	116	Behavioural disorder NOS	5	Estimated	Food and Drug Administration Center for Veterinary Medicine		5	5	Veterinarian	Other	20250101	20250101	Other	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027665	20250522	MSK	Cat	Excessive thirst		18	544	Excessive thirst	5	Estimated	Food and Drug Administration Center for Veterinary Medicine		5	5	Veterinarian	Other	20250101	20250101	Other	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027665	20250522	MSK	Cat	Sedation		18	111	Sedation	5	Estimated	Food and Drug Administration Center for Veterinary Medicine		5	5	Veterinarian	Other	20250101	20250101	Other	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-027665	20250522	MSK	Cat	Hyperthermia		18	1014	Hyperthermia	5	Estimated	Food and Drug Administration Center for Veterinary Medicine		5	5	Veterinarian	Other	20250101	20250101	Other	Unknown				NOT ASKED/NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Lethargy (see also Central nervous system depression in Neurological)		18	1018	Lethargy (see also Central nervous system depression in Neurological)	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Increased heart rate		18	193	Increased heart rate	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Hiding		18	2207	Hiding	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Dilated pupils		18	1414	Dilated pupils	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Death		18	984	Death	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Distress		18	114	Distress	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-033153	20250611	MSK	Cat	Vomiting		18	334	Vomiting	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian	Animal Owner	20250526	20250526	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020025	20250424	MSK	Cat	Application site scab		18	15	Application site scab	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020025	20250424	MSK	Cat	Drooling		18	292	Drooling	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020025	20250424	MSK	Cat	Restlessness		18	119	Restlessness	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-020025	20250424	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250401	20250401	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}			E173270	2026-04	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-017047	20250407	MSK	Cat	Application site hair loss		18	3	Application site hair loss	1	Actual	Food and Drug Administration Center for Veterinary Medicine	false	1	1	Other	Animal Owner	20250331	20250331	Other	Topical	{“numerator”: “1”, “numerator_unit”: “mL”, “denominator”: “1”, “denominator_unit”: “Animal”}	true		E186724	2026-06	Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025013	20250508	MSK	Cat	Nausea		18	1638	Nausea	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025013	20250508	MSK	Cat	Drooling		18	292	Drooling	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}
USA-USFDACVM-2025-US-025013	20250508	MSK	Cat	Not eating		18	1207	Not eating	1	Actual	Food and Drug Administration Center for Veterinary Medicine		1	1	Veterinarian		20250101	20250101	Veterinarian	Topical	{“numerator”: “1”, “numerator_unit”: “tube”, “denominator”: “1”, “denominator_unit”: “Animal”}	false	Indication Off-Label	NOT PROVIDED		Solution	QN02AE01	Buprenorphine	{“name”: “MSK”, “registration_number”: “USA-USFDACVM-N141547”}