Researcher Outreach: Buprenorphine Pharmacokinetics (Added May 2026)
We reached out to Colorado State University for publication on Zorbium® in guinea pigs, with the following questions: the rationale for off-label use in guinea pigs given the adverse event profile in cats; whether any unexpected effects or complications were observed during the study; whether the full text could be shared; and whether dark pigmentation or melanin content might influence transdermal drug absorption — given our observational finding of disproportionate fatalities in black and dark-coated cats. We are awaiting a response.

Ingredient Safety Concerns Analysis based on consultation with board-certified environmental toxicologist with pharmacy background



